Plenary Session 7: Year in Review

Plenary Session

Date/Time: Saturday, May 1, 2021 - 5:00 PM to 7:00 PM
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Description:

OA Clinical; Epidemiology and Therapy
Jonathan Quicke, Keele University
This year in review will be a personal selection of research highlights from the 15th April 2020 to 1st April 2021. An electronic database search will be carried out in Medline and Embase focussing on OA clinical and epidemiology research carried out in human adults. Studies of perceived high clinical importance and quality or controversy in the field will be selected. Studies and findings will be grouped into emerging themes to be discussed in the final presentation. The talk will conclude with a year in review infographic.

Imaging
Edwin Oei, Erasmus Medical College
In this session I will provide a narrative review of original research publications related to imaging advancements in osteoarthritis (OA) published in the English language in the past year (May 2020-April 2021). The review will encompass a variety of imaging modalities, including radiography, computed tomography (CT), magnetic resonance imaging (MRI), ultrasound, and nuclear imaging techniques, with a focus on validation, applied human research and image analysis using novel methodology such as deep learning.

Rehabilitation & Outcomes
Michael Bade PT, DPT, PhD, University of Colorado Anschutz Medical Campus
The purpose of this presentation will be to describe recent key developments in the rehabilitative management of individuals with osteoarthritis (OA).  A review of and critique of recent literature from an evidence-based perspective will be provided.  Additionally, future directions for rehabilitation will be discussed including the need to identify subgroups of individuals with OA for targeted intervention as well as the need for strategies to promote sustainability of interventions.

Mechanics in OA
Jaap Harlaar, Professor, Delft University of Technology
This presentation will review relevant developments In mechanics in OA in 2020. This comprises both insights in the role of tissue mechanics in OA etiology as well as applications of biomechanical analyses in patient care.

Biomarkers
Yves Henrotin, PhD, University of Liège
The joint use of OMICS methods, bioinformatics and biological fluids from large patient cohorts enabled significant progress in the discovery and qualification of biological markers in osteoarthritis. This lecture is a review of the advances made in this field during the period between April 2020 and April 2021.

Genetics, Genomics, Epigenetics
David Young, PhD, Newcastle University
This presentation will summarise the year in terms of research in OA in Genetics, Genomics and Epigenetics.

OA Biology
Yangzi Jiang, PhD, The Chinese University of Hong Kong
There is emerging awareness that subchondral bone remodeling plays important role in the development of osteoarthritis. This talk will summarize the recent investigations on the cellular and molecular mechanism of subchondral bone remodeling, and potential therapeutic targets related to OA subchondral bone remodeling, with the highlight of the new understandings of subchondral bone remodeling in OA in the year 2020, including the anatomical, cellular and molecular signatures in subchondral bone that identify different OA subtypes, and the clinical trials about regulating OA subchondral bone, and application of regenerative therapy on subchondral bone as potential OA interventions.

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