Plenary Session 3: Keynote Address: Mechanistic Insights into OA Pain

Plenary Session

Date/Time: Friday, April 30, 2021 - 1:00 PM to 2:45 PM
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Chronic Pain in Pre and Post Total Knee Arthroplasty
Based on a new set of experimental, quantitative, pain profiling bed-side tools approximately 40% of the OA patients can be characterized as pain hypersensitive and hence provides the opportunity to stratify and personalize the management regime.  Pain intensity and pain sensitization prior to total knee arthroplasty are some of the important predictive factors for why approximately 16% of the patient develop chronic post-operative pain.  Recently epigenetic modifications are found to make patients more vulnerable to develop chronic post-operative pain.  Revision surgery based on the indication pain will leave 80 % of the patients with more pain and more pain sensitization.  New management regimes are needed for managing chronic post-operative pain after total knee arthroplasty.  

Followed by abstract presentations.